Molecular pathology

Terminology description

The branch of medical science that deals mainly with evolutionary development of an organism, progress and diseases prevalence is referred as molecular pathology. This is used in biomedical research of genetic diseases. Molecular pathology is a subset branch of pathology which concerns mainly with diseases. In general, pathology refers to etiology study and disease pathogenesis by assessing cellular and molecular modifications of cells, tissues and organs. Modern face of pathology is molecular pathology and are referred as pathology of future. Molecular pathology is also widely used in the field of medical field, immunology, genetics and related fields. Molecular pathologists perform wide variety of tests to assess disease progression by analyzing DNA sequence and amino acid sequence with the help of biomarkers. For instance, genetic diseases like cancer origin can be predicted easily by molecular pathology research.  With the help of predictions made by molecular pathologists, oncologists can perform cancer screening, diagnosis and treatment.

Molecular mechanism

Molecular pathology helps in better understanding of molecular mechanism of diseases which increases at a constant speed.  It helps molecular pathologists to predict prognosis and diagnosis of disease and curative treatment. Molecular medicine is referred as personalized medicine.

Branches of molecular pathology

Major integral part of molecular pathology is divided in to two types as follows.

• Genomics
• Proteomics
  

Tools of molecular pathology

Molecular methods to interpret the gene and protein expression are tools of molecular pathology. With this tool, molecular pathologist helps in development of specific drugs. It is of two types, viz.

• Molecular biology: Analysis of protein and nucleic acids after extraction
• Molecular morphology: In situ molecular techniques are FISH, SISH and IHC (in situ proteomics)

Benefits of molecular pathology

Molecular biology benefits are

• Design of protein and nucleic acids
• Tissue banking information retrieval
• Genetic disease analysis
• Determination of chemical carcinogens
• Cell differentiation studies
• Diagnosis of abnormal growth of cells

Questions

• What is molecular pathology? How does it benefit biological research?
• What is the role of molecular pathologist?
• How molecular techniques promote cancer treatment?
• Explain mechanism of molecular reactions.